After googling many hours i found solution, meybe just workaround.
I change smt_relay_login in authentication section in file /etc/exim4/exim4.conf.template
(panel->server settings->edit exim4 or http:///edit/server/exim4/) to:
smtp_relay_login:
driver = plaintext
public_name = PLAIN
hide client_send = ^SMTP_RELAY_USER^SMTP_RELAY_PASS
… and it starts works.
Thanks to this document 33. SMTP authentication
Good Luck.