After updating to 1.4.5, my admin user seems to have lost admin privileges, or something to that effect. I cannot see any other users on the server and have no server level management links on the settings page.
Additionally, both the Add User and Packages links do nothing and lead right back to this identical page.
In regards to reporting this as a bug, I can confirm the same thing happened when upgrading my secondary server. I imagine this should probably be address in the upgrade/installation script.