Making a SMTP relay

I have managed to get port 25 opened on AWS, i’m running a mail server but I need to use one of the account as a no-reply account, and I want to add it to my services so they can automatically send emails.

Will this be possible?

Seems like I been blocked by spamphus, will try to get it unblocked.

Just create the no-reply account for you mail domain and if you don’t want to save received mail, select option to discard all mail when creating the account.

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You are probably trying to use Spamhaus lists from an open DNS resolver.