Yep, I have made countless raises and reboots. This issue already sucked up hours that might have been better invested splitting up our instance or something…
$ sysctl fs.file-max fs.aio-max-nr
fs.file-max = 70000
fs.aio-max-nr = 65536
Now trying your configuration hacks with rebuild via Force Reload From Template,
though these configurations should probably go into respective subfolders so they can easily be toggled.